According to the World
Cancer Research Fund report, India is the second highest country with ovarian
cancer cases after China. Every year over 47,000 cases are reported in India.
new studies and clinical practice suggest that lifestyle choices are a major
determinant of ovarian health. While genes and age remain strong risk factors,
modifiable lifestyle determinants such as physical activity and nutrition can
influence ovarian function, inflammation, and even the risk of cancer.
What is Ovarian Cancer?
According to
Dr.IndhraNedumaran, Senior Consultant, Gynaecology at MGM Cancer Institute in
Chennai, ovarian cancer, simply put, is a type of cancer where there is
uncontrollable growth of abnormal cells in the ovaries. They are caused due to
genetic changes that occur in a person’s lifetime. Alternatively, they can be
caused due to inherited genes.
In India, ovarian
cancer is the third most common cancer affecting women, the first two being
breast cancer and cervical cancer. "As ovarian cancer is typically
diagnosed only in its advanced stage, most of the time, it complicates the
treatment and cure," informs Dr Nedumaran.
Some of the possible
risk factors for developing ovarian cancer are early menarche (the first
period) and late menopause. Furthermore, research states that fluid released
during ovulation, the Follicular fluid, contains cytokines that damage the
epithelial DNA present in the fallopian tubes.
This predisposes a person to
cancer. "This risk factor provides the basis for using oral contraception
that prevents ovulation as a prophylaxis (preventive action) for ovarian
cancer," says the gynaecologist.
Factors Responsible for
Overian Cancer
Apart from menarche and
late menopause, Dr Nedumaran says that reproductive choices have an impact on
the appearance of ovarian cancer. Having a child before 25 years and
breastfeeding may reduce ovulation and thereby reduce the risk of ovarian
cancer. "It is advisable to have regular follow-ups for infertility and
infertility-treated patients it will help in early diagnosis and finding a
complete cure," recommends Dr Nedumaran.
Additionally, genetic
factors can also influence the presentation of ovarian cancer. "Genetic
screening can identify the risk factors and undertake precautionary measures
and procedures ranging from taking oral contraceptive pills to prophylactic
fallopian tube removal (Salpingectomy) to ovarian removal (oophorectomy),"
she says.
Another risk factor, Dr
Nedumaran says is obesity.
Obesity can be a result of genetic, environmental,
and physiological factors. Lifestyle, diet, and exercise also play an important
role in obesity. Obesity is often a risk factor for a host of other diseases,
including heart disease, liver disease, diabetes, and some cancers. For ovarian
cancer, too, obesity is a risk factor.
Lifestyle Modifications
that Can Prevent Overain Cancer
Usually, for most
people, obesity can be managed and moderated through lifestyle modification.
This includes having a diet rich in protein and fibre. Moreover, fruits and
vegetables should make up 50% of your meal. A low-carb diet will also aid this
endeavour. "Healthy eating habits, along with regular exercise, will help
reduce and maintain a normal BMI (Body Mass Index). Eating a balanced diet and
exercising regularly are the two pillars of sustainable obesity management.
This indirectly helps in reducing the risk of ovarian cancer," says Dr
Nedumaran.
According to Dr Dr N S
Saradha, Obstetrics, Gynaecology and IVF at SIMS Hospitals in Chennai, Regular
exercise can play an important role in preventing ovArian cancer.
"Exercise increases blood supply to the pelvic organs, enhances endocrine
equilibrium, and decreases insulin resistance, factors that can contribute to
ovarian failure if neglected," says Dr Saradha.
As individuals, we
often underestimate the impact of physical activity, and most women in Indian
do not even think exercise as their priority. Dr Saradha suggests at least 40
minutes of aerobic walk five times a week to "Moderate estrogen metabolism
and reduce levels of circulating growth factors that spur cell growth in the
ovaries."
Plant-based Diet
Apart from exercise, Dr
Saradha says a plant-based diet is equally potent.
Diets rich in whole grains,
legumes, cruciferous vegetables, berries, and healthy fats like flaxseed or
walnuts offer antioxidants and anti-inflammatory properties. She says,
cruciferous vegetables such as broccoli and kale are packed with
glucosinolates, which enhance hormonal detoxification pathways. Similarly, soy
foods and flaxseed contain phytoestrogens that can naturally help balance
estrogen levels without increasing risk. "These aren’t magic foods, but
when consumed consistently as part of a well-planned, plant-based diet, they
support long-term ovarian resilience," says Dr Saradha.
She says that
plant-based diets also contribute to lower body fat, "which reduces
peripheral aromatisation of androgens to estrogen, a process linked to ovarian
dysfunction and certain cancers. The anti-inflammatory and antioxidant
properties of such diets reduce inflammation and oxidative stress, both of
which are associated with tumor growth and progression in ovarian cancer."
Dr Nedumaran also
agrees that a plant-based diet can also reducing the risk of ovarian cancer.
She says that a plate where plants are the star goes a long way in improving
health. "Cruciferous veggies, fiber and flavonoids have anti-cancer
properties. Isoflavones in soy and soy-based products have been discovered to
reduce ovarian cancer risk. "Dairy and dairy-based products can be
avoided. Foods rich in trans-fat, like processed food and deep-fried dishes,
are another item to be checked off the list," suggests Dr Nedumaran.
Exercise with
Plant-based Diet, a combination to combat Ovarian Cancer
Experts say a good diet
plan, goes well with a good exercise plan.
They are inseparable. Physical
activity is shown to have reduced ovarian cancer risk and also helps in
maintain strength after a cancer diagnosis. It also aids in improving immunity
and overall health.
"Gynecologic
symptoms such as ovarian cysts and chronic inflammation are more common in
women with a high intake of processed meat and saturated fats. It’s not about
being perfect, it’s about being consistent. Eating well and exercising
consciously are powerful interventions we can all do. When initiated early on,
these habits can be protective not just for the ovaries, but for overall
health," says Dr Saradha.
On the other hand, Dr Nedumaran recommends
meeting a specialist to assess and understand your risk of ovarian cancer.
"This will also provide an understanding of the preventive measures
available. Further, it can help instigate lifestyle changes necessary to reduce
the risk of ovarian cancer," concludes the senior gynecologist.